Unless you live in the Wiregrass, stay off of Hwy. 231 (from Montgomery south to I-10) if at all possible. We drive this route practically EVERY week from Tallahassee to Tuscaloosa, but only because it's the least of several evils. Getting through Montgomery on 231 (to/from I-65) is a pain, especially during the weekday, and it doesn't get any better after that. There are several large towns and small cities (Ozark, Troy and Dothan) along the way. All have police depts., and Dothan, in particular, is a nightmare - 231 is THE road everybody takes (apparently) to get around the town. Through-traffic will just make this worse.
Plus, there are lots of rural county sheriffs (in addition to State Troopers AND Highway Patrolmen AND city officers) on I-10 between 231 and Jax that prey on lead-footed tourists. You've been warned.
My advice is to stick to the interstates:
- I-20 towards Atlanta. There isn't really any "good" way to get through the ATL. On Fridays, traffic starts picking up at around 3:00, peaks at about 6:00, and tapers off to "normal" insanity levels at about 7:00-8:00. If you can, time your trip to avoid the city completely between 4:00 and 7:00 (don't forget to add an hour for the time change). If you can't, when you get close, turn on the radio, look at your map, and listen for which routes to avoid. There are basically two choices:
(1) I-20 to the I-75 interchange downtown, or
(2) I-20 to I-285 South ("the Perimeter" in local lexicon), to I-75 South.
Whichever one you choose will depend on local conditions. Personally, I prefer the more direct downtown route, especially in the afternoon/evening. Downtown traffic may be horrendous (and it is, during the workday at least), but it keeps moving at a good clip, for the most part. Not for the faint of heart, though. By contrast, I-285 is usually a parking lot in the afternoons, clogged with commuters trying to get home.
- Once you clear Atlanta, continue South on I-75 , which will shoot you out onto I-10 near Lake City, FL.
- I-10 East to Jax.
RTR, and I'll see you there!